Product ID:M5005, MANGANESE CHLORIDE TETRAHYDRATE INSECT CELL (SUPDAT)
MSDS Date:01/01/1999
FSC:6810
NIIN:00N093248
Status Code:A
MSDS Number: CJWSJ

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

(ORAL, RAT) 1484

CAS: 13446-34-9

RTECS: OO9650000

LD50 LC50 Mixture:SEE INGREDIENT
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE EFFECTS: HARMFUL IF SWALLOWED.
MAY BE HARMFUL IF INHALED. MAY BE HARMFUL IF ABSORBED THROUGH THE
SKIN. CAUSES EYE AND SKIN IRRITATION. MATERIAL IS IRRITATING TO
MUCOUS MEMBRANES AND UPPER RESPIR ATORY TRACT. CHRONIC EFFECTS:
LABORATORYEXPERIMENTS HAVE SHOWN MUTAGENIC EFFECTS. MEN EXPOSED TO
MANGANESE DUSTS SHOWED A DECREASE IN FERTILITY. CHRONIC MANGANESE
POISONING PRIMARILY INVOLVES THE CENT RAL NERVOUS SYSTEM. EARLY
SYMPTOMS INCLUDE LANGUOR, SLEEPINESS AND WEAKNESS IN THE LEGS. A
STOLID MASK-LIKE APPEARANCE OF THE FACE, EMOTIONAL DISTURBANCES
SUCH AS UNCONTROLLABLE LAUGHTER AND A SPASTIC GAIT (EFFECTS OF
OVEREXPOSURE)
Effects of Overexposure:HEALTH HAZARDS: WITH TENDENCY TO FALL IN
WALKING ARE FINDINGS IN MORE ADVANCED CASES. HIGH INCIDENCE OF
PNEUMONIA HAS BEEN FOUND IN WORKERS EXPOSED TO THE DUST OR FUME OF
SOME MANGANESE COMPOUNDS. TAR GET ORGANS: CENTRAL NERVOUS SYSTEM,
LUNGS. TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL AND
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
ALSO, SEE TOXICOLOGICAL INFORMATION.

First Aid:EYES: IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS
AMOUNTS OF WATER FOR AT LEAST 15 MINUTES. SKIN: IN CASE OF CONTACT,
IMMEDIATELY WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER.
INHALATI ON: IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE
ARTIFICIAL RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
INGESTION: IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON
IS CONSCIO US. CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE
REUSE.

Extinguishing Media:NONCOMBUSTIBLE. USE EXTINGUISHING MEDIA APPROPRIATE
TO SURROUNDING FIRE CONDITIONS.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT TO PREVENT CONTACT WITH SKIN AND EYES.
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS, RUBBER BOOTS AND HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN
A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE
AREA AND WASH SPILL SI TE AFTER MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:DO NOT BREATHE DUST. DO NOT GET IN
EYES, ON SKIN, ON CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING. KEEP TIGHTLY CLOSED.

Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:EYE WASH AND DELUGE SHOWER MEETING ANSI
DESIGN CRITERIA . WEAR OTHER PROTECTIVE CLOTHING.
Supplemental Safety and Health
MFR'S TRADE NAME/PART NO: CULTURE TESTED. WASTE DISP METH: NEUTRALIZE
THE SOLUTION BEFORE FLUSHING DOWN THE DRAIN. OBSERVE ALL FEDERAL,
STATE AND LOCAL ENVIRONMENTAL REGULATIONS.

Melt/Freeze Pt:=58.C, 136.4F
Spec Gravity:2.010
Appearance and Odor:PINK CRYSTALS.

Stability Indicator/Materials to Avoid:YES
STRONG ACIDS. REACTS VIOLENTLY WITH: SODIUM, POTASSIUM, ZINC.
Stability Condition to Avoid:PROTECT FROM MOISTURE.
Hazardous Decomposition Products:HYDROGEN CHLORIDE GAS.

Waste Disposal Methods:THIS MATERIAL SHOULD BE DISSOLVED IN 1) WATER;
2) ACID SOLUTION OR 3) OXIDIZED TO A WATER-SOLUBLE STATE.
PRECIPITATE THE MATERIAL AS THE SULFIDE, ADJUSTING THE PH OF THE
SOLUTION TO 7 TO COMPLETE PREC IPITATION. FILTER THE INSOLUBLES AND
DISPOSE OF THEM IN A HAZARDOUS-WASTE SITE. DESTROY ANY EXCESS S
ULFIDE WITH SODIUM HYPOCHLORITE. (SUPDAT)

Toxicological Information:RTECS #: OO9650000. MANGANESE (II) CHLORIDE,
TETRAHYDRATE. TOXICITY DATA: ORL-RAT LD50: 1484 MG/KG EVHPAZ
10,95,1975. IRP-RAT LD50: 138 MG/KG EVHPAZ 10,95,1975. PAR-RAT
LD50: 225 MG/KG JINCAO 41,1507, 1979. IPR-MUS LD50: 144 MG/KG
TXAPA9 63,461,1982. SCU-MUS LD50: 320 MG/KG TOLED5 69,45,1993.
TARGET ORGAN DATA: PAPTERNAL EFFECTS (TESTES, EPIDIMYSIS, SPERM
DUCT). MATERNAL EFFECTS (OTHER EFFECTS ON F EMALE). EFFECTS ON
FERTILITY (POST-IMPLANTATION MORTALITY). EFFECTS ON EMBRYO OR FETUS
(FETOTOXICITY). SPECIFIC DEVELOPMENTAL ABNORMALITIES
(MUSCULOSKELETAL SYSTEM). ONLY SELECTED (OTHER INFO)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAILABLE. FED REG INFO: OSHA PEL (SHIPYARD):
CL 5 MG(MN)/M3 CFRGBR 29,1915.1000,1993. OSHA PEL (FED CONT): CL 5
MG(MN)/M3 CFRGBR 41,50-204.50,1994. OEL-AUSTRALIA: TWA 5 MG(MN)/M3
JAN 199 3. OEL-BELGIUM: TWA 5 MG(MN)/M3 JAN 1993. OEL-DENMARK: TWA
2.5 MG(MN)/M3 JAN 1993. OEL-FINLAND: TWA 2.5 MG(MN)/M3 JAN 1993.
OEL-HUNGARY: TWA 0.3 MG(MN)/M3; STEL 0.6 MG(MN)/M3 JAN 1993.
OEL-JAPAN: TWA 0.3 MG(MN)/M3 JAN 1993. OEL-THE NETHERLANDS: TWA 1
MG(MN)/M3 JAN 1993. OEL-POLAND: TWA 0.3 MG(MN)/M3 JAN 1993.
OEL-SWEDEN: TWA 1 MG(MN)/M3; STEL 2.5 MG(MN)/M3 (RESP DUST) JAN
1993. OEL-SWEDEN: TWA 2.5 MG(MN)/M3; (TRANSPORT INFO)

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION. ECOLOGICAL INFO: STEL 5 MG(MN)/M3 (TOTAL DUST) JAN
1993. OEL-UNITED KINGDOM: TWA 5 MG(MN)/M3 JAN 1993. OEL IN
BULGARIA, COLOMBIA, JORDAN, KOREA CHECK ACGIH TLV. OEL IN NEW
ZEALAND, SINGAPORE, VIETNAM CHECK ACGIH TLV. NOES 1983: HZD X4985;
NIS 3; TNF 110; NOS 5; TNE 3297; TFE 1033. EPA GENETOX PROGRAM
1988, POSITIVE: CELL TRANSFORM.-RLV F344 RAT EMBRYO.

SARA Title III Information:THIS PRODUCT IS SUBJECT TO SARA SECTION 313
REPORTING REQUIREMENTS - MANGANESE COMPOUNDS.
Federal Regulatory Information:EUROPEAN INFORMATION - CAUTION:
SUBSTANCE NOT YET FULLY TESTED. HARMFUL. R 22 HARMFUL IF SWALLOWED.
R 36/37/38 IRRITATING TO EYES, RESPIRATORY SYSTEM AND SKIN. R 40
POSSIBLE RISK OF IRREVERSIBLE EFFEC TS. S 26 IN CASE OF CONTACT
WITH EYES, RINSE IMMEDIATELY WITH PLENTY OF WATER AND SEEK MEDICAL
ADVICE. S 36 WEAR SUITABLE PROTECTIVE CLOTHING. REVIEWS, STANDARDS
AND REGULATIONS - OEL=MAK. ACGIH TLV-T WA 0.2 MG(MN)/M3 DTLVS
TLV/BEI,1997. MSHA STANDARD-AIR: CL 5 MG(MN)/M3 DTLVS 3,149,1971.
OSHA PEL (G EN INDU): CL 5 MG(MN)/M3 CFRGBR 29,1910.1000,1994. OSHA
PEL (CONSTRUC): CL 5 MG(MN)/M3 CFRGBR 29,1926.55,1994. (ECOLOGICAL
INFO)